Item Type | Name |
Concept
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Mice, Knockout
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Academic Article
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Thyrotropin regulation by thyroid hormone in thyroid hormone receptor beta-deficient mice.
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Academic Article
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Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone.
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Academic Article
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Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo.
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Academic Article
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Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency.
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Academic Article
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RXR receptor agonist suppression of thyroid function: central effects in the absence of thyroid hormone receptor.
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Academic Article
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Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice.
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Academic Article
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Hypothyroidism in thyroid transcription factor 1 haploinsufficiency is caused by reduced expression of the thyroid-stimulating hormone receptor.
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Academic Article
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Partial deficiency of thyroid transcription factor 1 produces predominantly neurological defects in humans and mice.
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Academic Article
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Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo.
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Academic Article
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Defective thyroglobulin storage in LDL receptor-associated protein-deficient mice.
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Academic Article
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Novel biological and clinical aspects of thyroid hormone metabolism.
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Academic Article
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Effects of maternal levels of thyroid hormone (TH) on the hypothalamus-pituitary-thyroid set point: studies in TH receptor beta knockout mice.
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Academic Article
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Importance of monocarboxylate transporter 8 for the blood-brain barrier-dependent availability of 3,5,3'-triiodo-L-thyronine.
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Academic Article
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A thyroid hormone analog with reduced dependence on the monocarboxylate transporter 8 for tissue transport.
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Academic Article
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Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion.
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Academic Article
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Thyrotrophin receptor signaling dependence of Braf-induced thyroid tumor initiation in mice.
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Academic Article
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Thyroid hormone receptor a and regulation of type 3 deiodinase.
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Academic Article
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Type 3 deiodinase deficiency results in functional abnormalities at multiple levels of the thyroid axis.
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Academic Article
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A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism.
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Academic Article
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Disruption of the melanin-concentrating hormone receptor 1 (MCH1R) affects thyroid function.
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Academic Article
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Role of type 2 deiodinase in response to acute lung injury (ALI) in mice.
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Academic Article
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Mice deficient in dual oxidase maturation factors are severely hypothyroid.
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Academic Article
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Dominant role of thyrotropin-releasing hormone in the hypothalamic-pituitary-thyroid axis.
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Academic Article
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In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice.
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Academic Article
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Increased sensitivity to thyroid hormone in mice with complete deficiency of thyroid hormone receptor alpha.
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Academic Article
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Genetic analysis reveals different functions for the products of the thyroid hormone receptor alpha locus.
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Academic Article
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Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice.
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Academic Article
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Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice.
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Academic Article
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Changes in thyroid status during perinatal development of MCT8-deficient male mice.
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Academic Article
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Placenta passage of the thyroid hormone analog DITPA to male wild-type and Mct8-deficient mice.
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Academic Article
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Inherited defects of thyroid hormone-cell-membrane transport: review of recent findings.
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Academic Article
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Mct8-deficient mice have increased energy expenditure and reduced fat mass that is abrogated by normalization of serum T3 levels.
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Academic Article
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The Thyroid Hormone Analog DITPA Ameliorates Metabolic Parameters of Male Mice With Mct8 Deficiency.
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Academic Article
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Hematopoietic Stem Cells Transplantation Can Normalize Thyroid Function in a Cystinosis Mouse Model.
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Academic Article
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Aberrant Cerebellar Development in Mice Lacking Dual Oxidase Maturation Factors.
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Academic Article
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Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.
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Academic Article
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Adeno Associated Virus 9-Based Gene Therapy Delivers a Functional Monocarboxylate Transporter 8, Improving Thyroid Hormone Availability to the Brain of Mct8-Deficient Mice.
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Academic Article
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TRH Action Is Impaired in Pituitaries of Male IGSF1-Deficient Mice.
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Academic Article
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Changes in Hepatic TRß Protein Expression, Lipogenic Gene Expression, and Long-Chain Acylcarnitine Levels During Chronic Hyperthyroidism and Triiodothyronine Withdrawal in a Mouse Model.
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Academic Article
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Fetal Exposure to High Maternal Thyroid Hormone Levels Causes Central Resistance to Thyroid Hormone in Adult Humans and Mice.
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Academic Article
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An Essential Physiological Role for MCT8 in Bone in Male Mice.
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Academic Article
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Homozygous loss-of-function mutations in SLC26A7 cause goitrous congenital hypothyroidism.
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Academic Article
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Noncanonical thyroid hormone signaling mediates cardiometabolic effects in vivo.
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Academic Article
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GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation.
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Academic Article
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NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland.
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Academic Article
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A Liver-Specific Thyromimetic, VK2809, Decreases Hepatosteatosis in Glycogen Storage Disease Type Ia.
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Academic Article
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Intracerebroventricular administration of the thyroid hormone analog TRIAC increases its brain content in the absence of MCT8.
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Academic Article
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Mice Hypomorphic for Keap1, a Negative Regulator of the Nrf2 Antioxidant Response, Show Age-Dependent Diffuse Goiter with Elevated Thyrotropin Levels.
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Academic Article
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Human Type 1 Iodothyronine Deiodinase (DIO1) Mutations Cause Abnormal Thyroid Hormone Metabolism.
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Academic Article
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Thyroidal Transcriptomic Profiles of Pathoadaptive Responses to Congenital Hypothyroidism in XB130 Knockout Mice.
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Academic Article
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Iodotyrosines Are Biomarkers for Preclinical Stages of Iodine-Deficient Hypothyroidism in Dehal1-Knockout Mice.
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